cees dekker - An Overview
cees dekker - An Overview
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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
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Non-equilibrium folding of specific DNA molecules recaptured approximately one thousand moments in the reliable condition nanopore
2010, formulated a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into stable-point out nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
A lot of similar developments adopted, where our group established various transistor variants including solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into little proof-of-principle electronic circuits.
Circulation-pushed rotary motors which include windmills and h2o wheels drive functional processes in human society. Despite the fact that samples of these rotary motors also aspect prominently in mobile biology, their artificial construction in the nanoscale has remained tough. Listed here we display move-pushed rotary movement of the self-structured DNA nanostructure that is docked onto a nanopore in a skinny solid-state membrane. An elastic DNA bundle self-assembles into a chiral conformation on phoretic docking on to the good-point out nanopore, and subsequently shows a sustained unidirectional rotary movement of up to ceesdekker 20 rev s−1.
The rotors harness Power from the nanoscale drinking water and ion flow that may be produced by a static chemical or electrochemical possible gradient during the nanopore, that happen to be set up via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-Arrange and operate autonomously in physiological disorders, suggesting strategies to constructing Electricity-transducing motors at nanoscale interfaces.
It absolutely was during this period that Dekker performed study on magnetic spin devices and on sounds in superconductors and semiconductors.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
2006, first demonstration of molecular sorting within a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and initially estimate of electrokinetic energy conversion within a nanofluidic channel
Let’s very first seem back again at the moment after you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the 1990s.
2013, controlled shaping of Are living bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations during the handedness of histone tetrasomes